Supramolecular colloidosomes: fabrication, characterisation and triggered release of cargo.

نویسندگان

  • Godwin Stephenson
  • Richard M Parker
  • Yang Lan
  • Ziyi Yu
  • Oren A Scherman
  • Chris Abell
چکیده

We report a one-step method of assembling supramolecular colloidosomes at the interface of microfluidic droplets. The self-assembly process utilises a versatile CB[8] host-guest system to reversibly crosslink polystyrene nanoparticles via a polyacrylamide linker. These micrometre-sized hollow structures can be loaded with water-soluble cargo during formation, which can then undergo triggered release.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Monodisperse stimuli-responsive colloidosomes by self-assembly of microgels in droplets.

We introduce a novel and versatile technique to fabricate monodisperse stimuli-responsive colloidosomes using stimuli-responsive microgel particles as building blocks, aqueous droplets as templates, and microfluidic devices to control the assembly. Our colloidosomes exhibit approximately 80% decrease in volume when actuated; thus, they can be of immense potential in applications that require ta...

متن کامل

Fabrication and characterisation of lavender oil - plant phospholipid based Sumatriptan succinate hybrid solid lipid nanoparticles.

Background:  Nanostructured lipid carriers (NLCs) of sumatriptan succinate (SS) were prepared by using lavender oil.  In ancient days, lavender oil was used for the treatment of a migraine. The natural anti-migraine agent, lavender oil, combined with an anti-migraine drug such as SS in a nano-formulation, will be a practical alternative approach in migraine therapy.  Objective: NLCs of sumatri...

متن کامل

Multiwalled functional colloidosomes made small and in large quantities via bulk emulsification.

Colloidosomes are attractive microcarriers for encapsulation and controlled release. If their shell is composed of multiple layers of particles they are very robust against defects, which ensures a well-defined permeability. So far most capsules with multilayer particle shells could only be assembled using microfluidic emulsification, a technique that offers unparalleled encapsulation control b...

متن کامل

Dual-responsive supramolecular colloidal microcapsules from cucurbit[8]uril molecular recognition in microfluidic droplets†

The macrocyclic host, cucurbit[8]uril, is used to facilitate cross-linking of colloidal particles and polymers in microdroplets resulting in thermoand photo-responsive supramolecular colloidal microcapsules. Methyl viologen-bearing colloidal particles were prepared using template polymerisation and combined with cucurbit[8]uril and an azobenzene-functionalised polymer within microfluidic drople...

متن کامل

Surface-immobilised micelles via cucurbit[8]uril-rotaxanes for solvent-induced burst release.

The fabrication, characterisation and controlled burst release of naphthol-functionalised micellar (NFM) nanostructures, which were grafted onto gold surfaces through cucurbit[8]uril (CB[8]) mediated host-guest interactions are described. NFMs undergo a facile change in morphology from micelles to diblock copolymers in direct response to exposure to organic solvents, including tetrahydrofuran (...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Chemical communications

دوره 50 53  شماره 

صفحات  -

تاریخ انتشار 2014